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Biostatistics blocking and confounding b.pharmacy 8th semester

      B.pharmacy 8th semester Biostatistics BP801T according to AKTU AND PCI SYALLABUS.    Today topic is blocking and confounding Blocking Technique has been utilized to handle Randomized Complete Block Design in the earlier Module.  As the 2k design is primarily used to screen factors/variables, often a very large number of experimental units are required to complete even one full replication. For an example, 26 design with six variables requires 64 experimental units to complete one full replication. In the 2k design of experiment, blocking technique is used when enough homogenous experimental units are not available.  Different batches do not necessarily mean non-homogeneity all the time. However, keeping track of the batch numbers as blocks (the statistical term) would provide an opportunity, if in case there is non-homogeneity from batch to batch.  Therefore, a block is defined by a homogenous large unit, including, raw materials, areas, pla...

Ndds unit 1 BP704T

Bp801t notes Ndds unit 1 notes BP704T Controlled drug delivery system        and polymers  Introduction Controlled drug delivery is one which delivers the drug at a predetermined rate, locally or systemically, for a specified period of time.    <meta name="purpleads-verification" content="7278f1721e67d8d0b0775d65"/> • Controlled release drug administration means not only prolongation of the duration of drug delivery, similar to the objective in sustained release and prolonged release, but the term also implies the predictability and reproducibility of drug release kinetics. Some important terminology  Sustained release drug delivery:  Any of the dosage form that maintains the therapeutic blood or tissue levels of drug by continuous release of medication for a prolonged period of time, after administration of a single dose. In case of injectable dosage forms it may vary from days to months. Bp801t biostatistics notes  https:/...

Glycolysis

Glycolysis,biochemistry   Introduction :-glycolysis is defined as the breakdown of one molecule of glucose of sux carbon atom into the two pyruvate of three carbon atom.  Glycolysis (glyco means glucose and lysis means breakdown or degradation). After the process of glycolysis the energy released is in the form of ATP andNADH. href="https://www.sigmatraffic.com/blog/10-tips-to-reduce-website-bounce-rate-what-s-the-average-bounce-rate?ref=130422">ReduceGlycolysis take place in the cytosol. Gylcolysis process is done in ten step in which many enzyme were used and energy utilised and energy generate. Overall reaction:- C6H12O6+2NAD+2ADP+2P---->2PYRUVIC ACID+2NADH+2ATP+2H Cycle of glycolysis:-           Step-I conversion of glucose to glucose 6 phospate Glucose is converted to glucose 6 phosphate with the use hexokinase enzyme.this step is energy consuming one ATP convert to ADP. step-II conversion of G6P to F6...