Healthians

Ndds unit 3 notes BP701t  Introduction Targeted drug delivery system Targeted drug delivery systems deliver drugs in the tissues of interest while lowering their relative concentrations in the remaining tissues. In 1906, scientist Ehrlich first proposed the concept of targeted drugs. As an alternative for effective therapeutics, targeted drugs were found to be particularly popular and effective, but the 'magic bullet' has proven difficult to implement clinically as a theoretical idea.  Approaches  Ndds unit 1 notes Drug targeting is the selective and efficient localization of pharmacologically-active moieties at predesigned targets while restricting their access to non-targets. This minimizes toxicity and maximizes the therapeutic index. Drugs are distributed to specific target sites by using a range of research outcomes. The methodology used is broadly divided into three categories: 1. Controlling the distribution of drug by incorporating the drug with a carrier mol...

Bp801t notes Ndds unit 1 notes BP704T Controlled drug delivery system        and polymers  Introduction Controlled drug delivery is one which delivers the drug at a predetermined rate, locally or systemically, for a specified period of time.    <meta name="purpleads-verification" content="7278f1721e67d8d0b0775d65"/> • Controlled release drug administration means not only prolongation of the duration of drug delivery, similar to the objective in sustained release and prolonged release, but the term also implies the predictability and reproducibility of drug release kinetics. Some important terminology  Sustained release drug delivery:  Any of the dosage form that maintains the therapeutic blood or tissue levels of drug by continuous release of medication for a prolonged period of time, after administration of a single dose. In case of injectable dosage forms it may vary from days to months. Bp801t biostatistics notes  https:/...

 Novel drug delivery systems BP704T NOTES UNIT II  Unit II syallabus Microencapsulation: Definition, advantages and disadvantages, microspheres/microcapsules, microparticles, methods of microencapsulation, applications. Mucosal Drug Delivery system: Introduction, Principles of bioadhesion / mucoadhesion, concepts, advantages and disadvantages, transmucosal permeability and formulation considerations of buccal delivery systems Implantable Drug Delivery Systems: Introduction, advantages and disadvantages, concept of implants and osmotic pump Some important questions from unit II 1. Define microparticles. Discuss the coaservation phase separation method for manufacturing of microparticles. 2. What is the size range of microparticles and nanoparticles? 3. Give merits of microencapsulation. Explain detailed methodology of emulsion technique for formulation of microcapsules. 4. Write a note on microencapsulation and give their applications. 5. Discuss the process of microencap...